CC Brown Snake Antivenom 10mL Vial

CC Brown Snake Antivenom 10mL Vial

BROWN SNAKE ANTIVENOM SOLUTION FOR INJECTION

1 NAME OF THE MEDICINE BROWN SNAKE ANTIVENOM (equine) as active ingredient.

2 QUALITATIVE AND QUANTITATIVE COMPOSITION BROWN SNAKE ANTIVENOM is prepared from the plasma of horses immunised with the venom of the eastern brown snake (Pseudonaja textilis). Each vial contains 1,000 units of antivenom which has been standardised to neutralise in vitro the average yield of venom from the brown snake. The product also contains 2.2 mg phenol, 8 mg sodium chloride and water for injections to 1.0 mL. Each vial contains ≤ 170 mg per mL of plasma protein of equine origin. The product volume is potency dependant thus it varies from batch to batch. Please refer to the product volume printed on the carton.

3 PHARMACEUTICAL FORM BROWN SNAKE ANTIVENOM is a concentrated solution for intravenous injection. It is a light straw coloured, slightly viscous transparent solution in a glass vial.

4 CLINICAL PARTICULARS

4.1 THERAPEUTIC INDICATIONS For the treatment of patients who exhibit manifestations of systemic envenoming following a bite by a snake of the genus Pseudonaja. This genus includes the eastern brown snake, the dugite and the gwardar (western brown snake).

4.2 DOSE AND METHOD OF ADMINISTRATION A proportion of people bitten by snakes have symptoms that are so mild that antivenom is not necessary. When there is evidence of systemic envenoming and it has been established that BROWN SNAKE ANTIVENOM is the appropriate treatment, the contents of one vial (1,000 units) should be administered slowly by intravenous infusion after dilution with Hartmann’s Solution or 0.9% w/v sodium chloride. Once diluted, BROWN SNAKE ANTIVENOM should be used immediately. Do not store diluted antivenom. The dose is the same for adults and children. The antivenom should be diluted 1 in 10, although a dilution of 1 in 5 may be more appropriate for patients at risk of fluid overload. Seek expert advice regarding dilution of antivenom to avoid fluid overload, as required. It should not be administered by the intramuscular route.

Brown Snake Antivenom